Leukemic infiltration of the ovary as an initial presentation of chronic myeloid leukemia in chronic phase

Introduction. Extramedullary sites of leukemic proliferation, harboring an adverse outcome, are rare and usually found in the blastic phase chronic myeloid leukemia. We report a case newly diagnosed patient with leukemia phase, infiltration right ovary on disease presentation. Case report. The presented abdominal pain, leukocytosis, anemia. A peripheral blood smear indicated leukemia, cytoreductive treatment was started. Due to worsening computed tomography done. It revealed cystic tumor ovary. surgically removed. Bone marrow examination confirmed diagnosis phase. Immunohistochemical analysis ovarian showed 5% blasts. treated imatinib for one year. failure, switched nilotinib. Allogeneic stem cell transplantation considered. Conclusion. This highlights critical role multidisciplinary team approach close monitoring achieve best possible outcome these patients.